@article {71, title = {Breaking the left-right symmetry in fluttering artificial cilia that perform nonreciprocal oscillations}, journal = {Meccanica}, volume = {In press}, year = {2024}, abstract = {

Recent investigations on active materi- als have introduced a new paradigm for soft robotics by showing that a complex response can be obtained from simple stimuli by harnessing dynamic instabili- ties. In particular, polyelectrolyte hydrogel filaments actuated by a constant electric field have been shown to exhibit self-sustained oscillations as a consequence of flutter instability. Owing to the nonreciprocal nature of the emerging oscillations, these\ artificial cilia\ are able to generate flows along the stimulus. Building upon these findings, in this paper we pro- pose a design strategy to break the left-right symme- try in the generated flows, by endowing the filament with a natural curvature at the fabrication stage. We develop a mathematical model based on morphoe- lastic rod theory to characterize the stability of the equilibrium configurations of the filament, proving the persistence of flutter instability. We show that the emerging oscillations are nonreciprocal and gener- ate thrust at an angle with the stimulus. The results we find at the level of the single cilium open new\ perspectives on the possible applications of artificial ciliary arrays in soft robotics and microfluidics.\ 

}, keywords = {Active matter, Artificial cilia, Flutter instability, left-right symmetry breaking, soft-robotics}, doi = {10.1007/s11012-024-01765-7}, author = {Ariel S. Boiardi and Roberto Marchello} } @article {70, title = {Flutter instability in solids and structures, with a view on biomechanics and metamaterials}, journal = {Proceedings of the Royal Society A}, volume = {479}, year = {2023}, pages = {20230523}, abstract = {

The phenomenon of oscillatory instability called "flutter" was observed in aeroelasticity and rotor dynamics about a century ago. Driven by a series of applications involving non-conservative elasticity theory at different physical scales, ranging from nanomechanics to the mechanics of large space structures and including biomechanical problems of motility and growth, research on flutter is experiencing a new renaissance. A review is presented of the most notable applications and recent advances in fundamentals, both theoretical and experimental aspects, of flutter instability and Hopf bifurcation. Open problems, research gaps and new perspectives for investigations are indicated.

}, keywords = {elasticity, Hopf bifurcation, non-conservative systems, non-Hermitian mechanics, non-holonomic constraints}, doi = {10.1098/rspa.2023.0523}, author = {Davide Bigoni and Francesco Dal Corso and Oleg N. Kirillov and Diego Misseroni and Giovanni Noselli and Andrea Piccolroaz} } @article {55, title = {Swimming Euglena respond to confinement with a behavioural change enabling effective crawling}, journal = {Nature Physics}, volume = {15}, year = {2019}, pages = {496-502}, abstract = {

Some euglenids, a family of aquatic unicellular organisms, can develop highly concerted, large-amplitude peristaltic body deformations. This remarkable behaviour has been known for centuries. Yet, its function remains controversial, and is even viewed as a functionless ancestral vestige. Here, by examining swimming Euglena\ gracilis in environments of controlled crowding and geometry, we show that this behaviour is triggered by confinement. Under these conditions, it allows cells to switch from unviable flagellar swimming to a new and highly robust mode of fast crawling, which can deal with extreme geometric confinement and turn both frictional and hydraulic resistance into propulsive forces. To understand how a single cell can control such an adaptable and robust mode of locomotion, we developed a computational model of the motile apparatus of Euglena cells consisting of an active striated cell envelope. Our modelling shows that gait adaptability does not require specific mechanosensitive feedback but instead can be explained by the mechanical self-regulation of an elastic and extended motor system. Our study thus identifies a locomotory function and the operating principles of the adaptable peristaltic body deformation of Euglena cells.

}, keywords = {crawling motility, Euglena gracilis, Metaboly, Spatial confinement}, doi = {10.1038/s41567-019-0425-8}, author = {Noselli, Giovanni and Beran, Alfred and Arroyo, Marino and DeSimone, Antonio} } @article {52, title = {Kinematics of flagellar swimming in Euglena gracilis: Helical trajectories and flagellar shapes}, journal = {Proceedings of the National Academy of Sciences of USA}, volume = {114}, year = {2017}, pages = {13085{\textendash}13090}, abstract = {

The flagellar swimming of euglenids, which are propelled by a single anterior flagellum, is characterized by a generalized helical motion. The 3D nature of this swimming motion, which lacks some of the symmetries enjoyed by more common model systems, and the complex flagellar beating shapes that power it make its quantitative description challenging. In this work, we provide a quantitative, 3D, highly resolved reconstruction of the swimming trajectories and flagellar shapes of specimens of Euglena gracilis. We achieved this task by using high-speed 2D image recordings taken with a conventional inverted microscope combined with a precise characterization of the helical motion of the cell body to lift the 2D data to 3D trajectories. The propulsion mechanism is discussed. Our results constitute a basis for future biophysical research on a relatively unexplored type of eukaryotic flagellar movement.\ 

}, keywords = {3D flagellum shapes, Euglena gracilis, helical trajectories, microscopy imaging, microswimmers}, doi = {10.1073/pnas.1708064114}, author = {Massimiliano Rossi and Giancarlo Cicconofri and Alfred Beran and Giovanni Noselli and Antonio DeSimone} }